[HTML][HTML] Combined treatment with amlodipine and atorvastatin calcium reduces circulating levels of intercellular adhesion molecule-1 and tumor necrosis factor-α in …

Z Huang, C Chen, S Li, F Kong, P Shan… - Frontiers in Aging …, 2016 - frontiersin.org
… in the distributions of clinical and metabolic characteristics of study … to benefit from treatment
with single-pill combination of … large relative reductions in the rates of cardiovascular events …

Clinical update: cardiovascular disease in diabetes mellitus: atherosclerotic cardiovascular disease and heart failure in type 2 diabetes mellitus–mechanisms …

CC Low Wang, CN Hess, WR Hiatt, AB Goldfine - Circulation, 2016 - Am Heart Assoc
… between the inflammatory, metabolic, and vascular pathways… rates of add-on statin use in
the placebo-assigned treatment … use of irbesartan versus amlodipine or placebo in addition to …

Simvastatin preconditioning confers neuroprotection against hypoxia-ischemia induced brain damage in neonatal rats via autophagy and silent information regulator 1 …

S Carloni, W Balduini - Experimental Neurology, 2020 - Elsevier
… of the PC-like effect of statins in brain tissue, supporting their … Autophagy is essential for
reprogramming the metabolism … O 2 (70/30%) mixture, and subjected to permanent ligation of …

Management of the metabolic syndrome and the emerging role of nutraceutical

G Odoh, JO Edah, JE Ojobi, JN Uwakwe… - … Journal of Medicine, 2019 - ajol.info
… media of the carotid artery as a surrogate for atherosclerosis-have … When used in combination
with statin therapy, fibrates … effect of quercetin in obese zucker rats. The study found that …

Pleiotropic and adverse effects of statins—do epigenetics play a role?

SC Allen, CDS Mamotte - Journal of Pharmacology and Experimental …, 2017 - ASPET
… are competitive inhibitors of HMG-CoA reductase, the rate-… In a rabbit model of atherosclerosis,
atorvastatin treatmentstatin users had raised levels due to underlying metabolic or …

Atorvastatin prevents the neuron loss in the hippocampal dentate gyrus region through its anti-oxidant and anti-apoptotic activities

S Yadollah-Damavandi, ZN Sharifi… - CNS & Neurological …, 2021 - ingentaconnect.com
… of an artery due to atherosclerosis, thromboembolism, or both [3]. … were tested on metabolic
syndrome in Zucker fatty rats, and it … treatment with amlodipine plus atorvastatin in Zucker

Mechanistic insight on autophagy modulated molecular pathways in cerebral ischemic injury: from preclinical to clinical perspective

P Kalra, H Khan, A Kaur, TG Singh - Neurochemical Research, 2022 - Springer
… Hence, making the cells switch to anaerobic metabolism in the affected region results in less
… reported that atorvastatin exhibits a neuroprotective effect when administered in rats with …

Psychopharmacology and cardiovascular disease

IL Piña, KE Di Palo, HO Ventura - Journal of the American College of …, 2018 - jacc.org
… Some of the effects are mediated by heart rate and acute blood pressure … the metabolism
of midazolam, which can lead to prolonged sedation. Concurrent administration of atorvastatin

Obesity and stroke: Can we translate from rodents to patients?

MJ Haley, CB Lawrence - … Cerebral Blood Flow & Metabolism, 2016 - journals.sagepub.com
… of stroke suffers benefit from tPA treatment. Furthermore, … (eg atherosclerosis), diabetes,
infection or metabolic syndrome/… db/db mice, and Zucker rats) rapidly gain weight because they …

Sodium-glucose cotransporter 2 inhibitors (SGLT2i): their role in cardiometabolic risk management

N Katsiki, DP Mikhailidis… - Current pharmaceutical …, 2017 - ingentaconnect.com
… Conclusion: Multiple metabolic benefits may account for the … β-blockers or calcium channel
blockers compared with those … pressure in obese rats suffering from the metabolic syndrome. …